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Frovatriptan is a selective agonist for serotonin (5-HT1B and 5-HT1D receptors) in cranial arteries. It causes vasoconstriction, reducing sterile inflammation associated with antidromic neuronal transmission. This action correlates with relief from migraine pain.
By narrowing blood vessels around the brain, frovatriptan blocks pain signals from being sent to the brain. It also stops the release of certain natural substances that cause pain, nausea, and other migraine symptoms.
Frovatriptan may not be suitable for everyone. Avoid taking these tablets if you are allergic to frovatriptan or any of the other listed ingredients.
These tablets contain a small amount of lactose, a type of sugar. If your healthcare provider has informed you that you have an intolerance to certain sugars, consult them before using frovatriptan.
Do not take this medicine if you have any of the following conditions:
Before taking this medicine, discuss with your doctor or Pharmacy Advance if you are a heavy smoker, taking smoking-cessation medicines, or if you are a woman in post-menopause or a man over 40 years of age.
One tablet to be taken, followed by ONE tablet after at leasts 4 hours if required. To be taken only if migraine recurs.
Patients who have not responded to the first dose should not take a second dose for the same attack.
Max of TWO tablets (5mg) per day.
Active Ingredient
Frovatriptan succinate monohydrate
Inactive Ingredients
See the patient information leaflet for a list of inactive ingredients.
For more detailed information on potential side effects, please consult the patient information leaflet. If you experience any side effects, including those not listed in the leaflet, consider reporting them through the MHRA Yellow Card Scheme.
Serious side effects require immediate medical attention. If you notice signs of a severe allergic reaction (such as facial and throat swelling, skin rash, breathing difficulties, or loss of consciousness), seek emergency help.
If you experience intense chest pressure or pain extending to the throat after taking Frovatriptan, contact your healthcare provider and avoid further doses of the medication
Frovatriptan is most effective when taken at the onset of the headache phase of a migraine. It should not be used as a preventive measure for migraines. If you find that your symptoms do not improve after taking frovatriptan, do not take an additional dose. For optimal results, use frovatriptan as directed at the first sign of a migraine headache.
What sets frovatriptan apart is its unusually long half-life. This means it remains active in the body for an extended period. If you experience migraines that recur within a day or two, frovatriptan could be particularly beneficial.
Both frovatriptan and sumatriptan are effective for treating migraines, but they have some differences:
Frovatriptan remains effective for longer periods due to its longer half-life. However, this longer duration also means it has a slower onset of relief (takes a longer time to work).
Sumatriptan has a shorter half-life, leading to faster onset of action and takes less time to work.It’s one of the most common triptans used for migraines.